Selected Publications
Vilardo, E.*, Amman, F., Toth, U., Kotter, A., Helm, M., and Rossmanith, W.*. 2020. Functional characterization of the human tRNA methyltransferases TRMT10A and TRMT10B. Nucleic Acids Res. doi: 10.1093/nar/gkaa353. *corresponding author.
Vilardo, E., Nachbagauer, C., Buzet, A., Taschner, A., Holzmann, J., and Rossmanith, W. 2012. A subcomplex of human mitochondrial RNase P is a bifunctional methyltransferase–extensive moonlighting in mitochondrial tRNA biogenesis. Nucleic Acids Res 40, 11583-11593. doi.org/10.1093/nar/gks910
Vilardo, E., and Rossmanith, W. 2015. Molecular insights into HSD10 disease: impact of SDR5C1 mutations on the human mitochondrial RNase P complex. Nucleic Acids Res 43, 5112-5119. doi.org/10.1093/nar/gkv408
Hoffmann, A., Fallmann, J., Vilardo, E., Mörl, M., Stadler, P.F. and Amman, F. 2018 Accurate mapping of tRNA reads. Bioinformatics, 34, 1116-1124. doi.org/10.1093/bioinformatics/btx756
Falk, M.J, Gai, X., Shigematsu, M., Vilardo, E., Takase, R., McCormick, E., Christian, T., Place, E., Pierce, E.A., Consugar, M., Gamper, H.B., Rossmanith, W., Hou, Y-M. 2016. A novel HSD17B10 mutation impairing the activities of the mitochondrial RNase P complex causes X-linked intractable epilepsy and neurodevelopmental regression. RNA Biol., 13:5, 477-485. doi.org/10.1080/15476286.2016.1159381
Hoffmann, A., Fallmann, J., Vilardo, E., Mörl, M., Stadler, P.F. and Amman, F. 2018 Accurate mapping of tRNA reads. Bioinformatics, 34, 1116-1124. doi.org/10.1093/bioinformatics/btx756
Falk, M.J, Gai, X., Shigematsu, M., Vilardo, E., Takase, R., McCormick, E., Christian, T., Place, E., Pierce, E.A., Consugar, M., Gamper, H.B., Rossmanith, W., Hou, Y-M. 2016. A novel HSD17B10 mutation impairing the activities of the mitochondrial RNase P complex causes X-linked intractable epilepsy and neurodevelopmental regression. RNA Biol., 13:5, 477-485. doi.org/10.1080/15476286.2016.1159381
Vilardo, E., and Rossmanith, W. 2015. Molecular insights into HSD10 disease: impact of SDR5C1 mutations on the human mitochondrial RNase P complex. Nucleic Acids Res 43, 5112-5119. doi.org/10.1093/nar/gkv408
Vilardo, E., and Rossmanith, W. 2013. The Amyloid-β-SDR5C1(ABAD) Interaction Does Not Mediate a Specific Inhibition of Mitochondrial RNase P. PLoS ONE 8, e65609. doi.org/10.1371/journal.pone.0065609
Vilardo, E., Nachbagauer, C., Buzet, A., Taschner, A., Holzmann, J., and Rossmanith, W. 2012. A subcomplex of human mitochondrial RNase P is a bifunctional methyltransferase–extensive moonlighting in mitochondrial tRNA biogenesis. Nucleic Acids Res 40, 11583-11593. doi.org/10.1093/nar/gks910
Vilardo, E., Barbato, C., Ciotti, M., Cogoni, C., and Ruberti, F. 2010. MicroRNA-101 regulates amyloid precursor protein expression in hippocampal neurons. J Biol Chem 285, 18344-18351. doi.org/10.1074/jbc.M110.112664
Barbato, C., Ruberti, F., Pieri, M., Vilardo, E., Costanzo, M., Ciotti, M.T., Zona, C., and Cogoni, C. 2010. MicroRNA-92 modulates K(+) Cl(-) co-transporter KCC2 expression in cerebellar granule neurons. J Neurochem 113, 591-600. doi.org/10.1111/j.1471-4159.2009.06560.x