Groups in the research area Cell and Tissue Biology focus their research on:
- Tumour Microenvironment and Signalling Pathways (Abraham/Zins),
- the biology of Trophoblast Stem Cells (Latos),
- the effects of Chromatin Modifications on the Homeostasis of the Epidermis (Seiser),
- the Identification of Novel Mutations in familial autosomal recessive and dominant Orphan Diseases (Lucas), and
- Chromatin Organisation and its influence on gene expression during Differentiation (Schöfer/Weipoltshammer)
- the molecular processes resulting in particular Protein Aggregate Myopathies (Winter)
Groups in the research area Developmental Biology focus their research on:
- Host-Symbiont Interactions during evolution (Miller),
- the Biology of Aging (Pusch),
- the functional and dynamic Architecture of Chromatin during Development and Differentiation (Schöfer/Weipoltshammer)
- the embryo intrinsic epigenetic reprogramming that underlies Early Cell Fate Decisions in early mammalian embryogenesis (Wossidlo/Arand).
Groups in the research area Molecular Genetics and Orphan Diseases focus their research on
- Neuromuscular and Neurodegenerative Diseases (Bittner/Schmidt),
- the Development of Novel Therapeutic Strategies for Orphan Diseases (Lucas),
- human RNA Processing Enzymes and their Involvement in Disease (Rossmanith)
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the molecular processes resulting in particular Protein Aggregate Myopathies (Winter)
Groups in the research area Epigenetics and RNA Biology focus their research on:
- the Design and Development of Programmable Chemical Probes that can bind specific RNA sequences for the selective release of fluorescent reporters or drugs within cells (Goldeck),
- the functional consequences of RNA Editing Mechanisms (Jantsch),
- functional and evolutionary long- and short-term Dynamics of Mobile Genetic Elements (Miller),
- Chromatin Dynamics during the Aging process (Pusch),
- the Biology of Mitochondrial RNA Processing enzymes (Rossmanith),
- the Impact of RNA Modifications on RNA stability and RNA function (Schaefer),
- the role of HDACs in the Control of Cellular Identity (Seiser),
- (Epi)transcriptomic Changes in Inflammation and Host-Microbiome Crosstalk (Vesely/Gawish)
- the influence of Specific RNA modifications on tRNA Structure and Function (Vilardo),
- the Epigenetic Reprogramming of Cellular Potency in early embryogenesis and stem cell biology (Wossidlo/Arand).