PUBLICATIONS
- Vcelkova T, Reiter W, Zylka M, Hollenstein DM, Schuckert S, Hartl M, Seiser C. GSE1 links the HDAC1/CoREST co-repressor complex to DNA damage. Nucleic Acids Res. 2023 Nov 27;51(21):11748-11769. doi: 10.1093/nar/gkad911. PMID: 37878419
- Hess L*, Moos V*, Lauber AA, Reiter W, Schuster M, Hartl N, Lackner D, Boenke T, Koren A, Guzzardo PM, Gundacker B, Riegler A, Vician P, Miccolo C, Leiter S, Chandrasekharan MB, Vcelkova T, Tanzer A, Jun JQ, Bradner J, Brosch G, Hartl M, Bock C, Bürckstümmer T, Kubicek S, Chiocca S, Bhaskara S, Seiser C. (2022). A toolbox for class I HDACs reveals isoform specific roles in gene regulation and protein acetylation. PLoS Genet. 2022 Aug 22;18(8):e1010376. doi:10.1371/journal.pgen.1010376 PMID: 35994477
- Beck, MA*; Fischer, H*; Grabner, LM; Groffics, T; Winter, M, Tangermann, S, Meischel, T; Barbara Zaussinger-Haas, B; Wagner, P; Fischer, C; Folie, C; Arand, J; Schöfer, C; Ramsahoye, B; Lagger, S; Machat, G; Eisenwort, G; Schneider, S; Podhornik, A; Kothmayer, M; Reichart, U; Glösmann, M; Tamir, I; Mildner, M; Sheibani-Tezerji, R; Kenner, L; Petzelbauer, P; Egger, G; Sibilia,M; Ablasser, A; Seiser, C (2021). DNA hypomethylation leads to cGAS-induced autoinflammation in the epidermis. EMBO J; 40(22):e108234. (* equally contributing first authors) PMID: 34586646
- Fischer H, Tschachler E, Eckhart L. Pangolins Lack IFIH1/MDA5, a Cytoplasmic RNA Sensor That Initiates Innate Immune Defense Upon Coronavirus Infection. Front Immunol; 2020, 11:939. doi: 10.3389. PMID: 32574256
- Fischer H, Buchberger M, Napirei M, Tschachler E, Eckhart L. Inactivation of DNase1L2 and DNase2 in keratinocytes suppresses DNA degradation during epidermal cornification and results in constitutive parakeratosis. Sci Rep; 2017,7:6433, doi: 10.1038/s41598-017-06652-8. PMID: 28743926
- Fischer H, Fumicz J, Rossiter H, Napirei M, Buchberger M, Tschachler E, Eckhart L. Holocrine Secretion of Sebum Is a Unique DNase2-Dependent Mode of Programmed Cell Death. J Invest Dermatol; 2017, 137:587-594, doi: 10.1016/j.jid.2016.10.017
- Sawicka, A; Hartl, D; Goiser, M; Pusch, O; Stocsits, R; Tamir, I; Mechtler, K; Seiser, C (2014). H3S28 phosphorylation is a hallmark of the transcriptional response to cellular stress. GENOME RES; 24(11):1808-20. PMID: 25135956
- Hagelkruys, A*; Lagger, S*; Krahmer, J; Leopoldi, A; Artaker, M; Pusch, O; Zezula, J; Weissmann, S; Xie, Y; Schöfer, C; Schlederer, M; Brosch, G; Matthias, P; Selfridge, J; Lassmann, H; Knoblich, JA; Seiser, C (2014). A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog. DEVELOPMENT; 141(3):604-16. PMID: 24449838
- Boucheron N, Tschismarov R, Göschl L, Moser MA, Lagger S, Sakaguchi S, Winter M, Lenz F, Vitko D, Breitwieser FP, Müller L, Hassan H, Bennett KL, Colinge J, Schreiner W, Egawa T, Taniuchi I, Matthias P, Seiser C*, Ellmeier W.* (2014). CD4(+) T cell lineage integrity is controlled by the histone deacetylases HDAC1 and HDAC2. NAT IMMUNOL; 15(5):439-48. PMID: 24681565 (* equally contributing senior authors)
- Fischer H, Langbein L, Reichelt J, Praetzel-Wunder S, Buchberger M, Ghannadan M, Tschachler E, Eckhart L. Loss of keratin K2 expression causes aberrant aggregation of K10, hyperkeratosis and inflammation. J Invest Dermatol; 2014, 134:2579-88, doi: 10.1038/jid.2014.197
- Fischer H, Szabo S, Scherz J, et al. Essential Role of the Keratinocyte-Specific Endonuclease DNase1L2 in the Removal of Nuclear DNA from Hair and Nails. J Invest Dermatol; 2011,131:1208-15, doi: 10.1038/jid.2011.13, PMID: 21307874
- Winter, M*; Moser, MA*; Meunier, D; Fischer, C; Machat, G; Mattes, K; Lichtenberger, BM; Brunmeir, R; Weissmann, S; Murko, C; Humer, C; Meischel, T; Brosch, G; Matthias, P; Sibilia, M; Seiser, C (2013). Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis. EMBO J; 32(24):3176-91. PMID: 24240174