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Publications

Ablasser A, Goldeck M, Cavlar T, Deimling T, Witte G, Rohl I, Hopfner KP, Ludwig J, Hornung V. cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING. Nature 2013, 498(7454): 380-384.

Goldeck M, Tuschl T, Hartmann G, Ludwig J. Efficient solid-phase synthesis of pppRNA by using product-specific labeling. Angewandte Chemie 2014, 53(18): 4694-4698.

Goubau D*, Schlee M*, Deddouche S, Pruijssers AJ, Zillinger T, Goldeck M, Schuberth, C, Van der Veen, AG, Fujimura, T, Rehwinkel, J et al. Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates. Nature 2014, 514(7522): 372-375.

Herzner AM*, Hagman CA*, Goldeck M, Wolter S, Kübler K, Wittman S, Gramberg T, Andreeva L, Hopfner KP, Mertens C et al. Sequence-specific activation of cGAS by Y-form DNA structures as found in primary HIV-1 cDNA. Nature Immunology 2015, 16(10): 1025-33.

Engel C, Brugmann G, Lambing S, Muhlenbeck LH, Marx S, Hagen C, Horvath D, Goldeck M, Ludwig J, Herzner AM et al. RIG-I resists hypoxia-induced immunosuppression and dedifferentiation. Cancer Immunology Research 2017, 5(6): 455-467.