Selected Publications
- Zrelski MM, Hösele S, Kustermann M, Fichtinger P, Kah D, Athanasiou I, Esser PR, Wagner A, Herzog R, Kratochwil K, Goldmann WH, Kiritsi D, and Winter L. Plectin deficiency in fibroblasts deranges intermediate filament and organelle morphology, migration, and adhesion. J Invest Dermatol. 2023, Sep 15:S0022-202X(23)02585-X. doi: 10.1016/j.jid.2023.08.020
- Winter L, Staszewska-Daca I, Zittrich S, Elhamine F, Zrelski MM, Schmidt K, Fischer I, Jüngst C, Schauss A, Goldmann WH, Stehle R, and Wiche G. Z-disk-associated plectin (isoform 1d): spatial arrangement, interaction partners, and role in filamin C homeostasis. Cells. 2023, Apr 26;12(9):1259. doi: 10.3390/cells12091259
- Winter L, Kustermann M, Ernhofer B, Höger H, Bittner RE, and Schmidt WM. Proteins implicated in muscular dystrophy and cancer are functional constituents of the centrosome. Life Science Alliance. 2022 Jul 5:5(11). doi: 10.26508/lsa.202201367
- Zrelski, MM, Kustermann M, and Winter L. Muscle-related plectinopathies. Cells. 2021 Sep 19;10(9):2480. doi: 10.3390/cells10092480
- Valencia RG, Mihailovska E, Winter L, Bauer K, Fischer I, Walko G, Jorgacevski J, Potokar M, Zorec R, and Wiche G. Plectin dysfunction in neurons lead to tau accumulation on microtubules affecting neuritogenesis, organelle trafficking, pain sensitivity and memory. Neuropathol Appl Neurobiol. 2021 Feb;47(1):73-95. doi: 10.1111/nan.12635; equal contribution
- Winter L, Unger A, Berwanger C, Spörrer M, Türk M, Chevessier F, Strucksberg KH, Schlötzer-Schrehardt U, Wittig I, Goldmann WH, Marcus K, Linke WA, Clemen CS, and Schröder R. Imbalances in protein homeostasis caused by mutant desmin. Neuropathol Appl Neurobiol. 2019 Aug;45(5):476-494. doi: 10.1111/nan.12516
- Winter L, Wittig I, Peeva V, Eggers B, Heidler J, Chevessier F, Kley RA, Barkovits K, Strecker V, Berwanger C, Herrmann H, Marcus K, Kornblum C, Kunz WS, Schröder R, and Clemen CS. Mutant desmin substantially perturbs mitochondrial morphology, function and maintenance in skeletal muscle. Acta Neuropathol. 2016 Sep;132(3):453-73. doi: 10.1007/s00401-016-1592-7; equal contribution
- Winter L, Türk M, Harter PN, Mittelbronn M, Kornblum C, Norwood F, Jungbluth H, Thiel CT, Schlötzer-Schrehardt U, and Schröder R. Downstream effects of plectin mutations in epidermolysis bullosa simplex with muscular dystrophy. Acta Neuropathol Commun. 2016, Apr27;4(1):44. doi: 10.1186/s40478-016-0314-7; equal contribution
- Winter L, Kuznetsov AV, Grimm M, Zeöld A, Fischer I, and Wiche G. Plectin isoform P1b and P1d deficiencies differentially affect mitochondrial morphology and function in skeletal muscle. Hum Mol Genet. 2015 Aug 15;24(16):4530-44. doi: 10.1093/hmg/ddv184
- Winter L, Staszewska I, Mihailovska E, Fischer I, Goldmann WH, Schröder R, and Wiche G. Chemical chaperone ameliorates pathological protein aggregation in plectin-deficient muscle. J Clin Invest. 2014 Mar 3;124(3):1144-57. doi: 10.1172/JCI71919